A recent clinical trial has shown that one vegetable extract may have astounding positive effects on those with autism – broccoli extract.
The US Centers for Disease Control tells the world that there is no treatment for autism spectrum disorder (ASD). But now that one in every 68 children is showing symptoms of the disorder (a huge spike since the year 2000), you would think that a clinical trial involving a simple, natural food-based supplement would be front page news. This, however, is not the world we live in, so you likely haven’t heard about a possible solution for autism that doesn’t rely on pharmaceutical medication – until now.
Along with an extensive Autism Spectrum Disease research database at GMI, there is evidence suggesting that broccoli extract (along with avoiding heavy metals, minimizing glyphosate exposure, and eradicating the diet of gluten) shows promise in improving ASD.
The active ingredient in broccoli that seems to help is called sulforaphane, a molecule found in cruciferous vegetables such as broccoli, cabbage, and Brussels sprouts.
A groundbreaking study published in 2014 in The Proceedings of the National Academy of Sciences USA titled, “Sulforaphane treatment of autism spectrum disorder (ASD),” found that a broccoli sprout extract significantly improved the behavior of boys and men (those who most often suffer from autism). Sulforaphane was selected, in part, because its physiological effects are well characterized and ideal for those with ASD:
“Dietary sulforaphane, of recognized low toxicity, was selected for its capacity to reverse abnormalities that have been associated with ASD, including oxidative stress and lower antioxidant capacity, depressed glutathione synthesis, reduced mitochondrial function and oxidative phosphorylation, increased lipid peroxidation, and neuroinflammmation.”
The placebo-controlled, randomized pilot study of 44 males, ages 13-27, showed that after 18 weeks of treatment with a sulforaphane-rich broccoli sprout extract, 46% had noticeable improvements in social interactions and 42% has improvements in verbal communication. More than half of all participants also showed a decrease in irritability, hyperactivity, and repetitive movements.
Of note, once treatment with broccoli extract stopped, most of the behaviors associated with autism returned. For more details on the study, read a Medscape report, including an interview with the study’s lead researcher.
The dosing schedule was determined by body weight:
- 100 lbs or less: one capsule containing 50 µmol (232 mg) of sulforaphane-rich broccoli extract was given daily
- 101–199 lbs, 100 µmol (two capsules of 232 mg each) of sulforaphane-rich broccoli extract was given daily
- More than 200 lbs: 150 µmol (three capsules of 232 mg each) of sulforaphane-rich broccoli extract was given daily
Sulforaphane happens to be one of the most extensively studied and promising natural substances in existence.
Consider that sulforaphane concentrations are several hundred times higher in the broccoli sprouts versus mature broccoli. This may very well be why the extract is therapeutic.
4 thoughts on “Clinical Trial: Vegetable Extract Competes with Drugs in the Treatment of Autism”
I can’t believe this article does not point out the huge advantage of using Broccoli sprouts in place of Broccoli to obtain one’s daily dose of sulforaphane. There are many medical studies which discuss the use of Broccoli Sprouts over Broccoli (or any other sulforaphane-containing cruciferous vegetable) because as reported, an equal serving size of 4-day Broccoli Sprouts delivers up to 75 times the level of sulforaphane of broccoli. Read this again! Why would anyone want to food around with trying to eat so much Broccoli, or to buy expensive Broccoli powders and figure out how to consume that? This Broccoli Sprouts discovery is also at the root of why so much alternative medicine advice does not work for many people who try the idea without discernable results — the correct dosage level is hard to reach without using the higher concentration food source. I have been consuming 1-2 cups Broccoli Sprouts for almost a year to reverse my Breast & Brain Cancer. Broccoli Sprout Juice has been shown to outperform the world’s #1 Chemotherapy Agent – Tamoxofen. Read that again! My Breast Cancer is gone, but still working on the Ocular/Brain Cancer. But listen to this! I am also on the Autism Spectrum (Aspergers end) and can verify that I noticed significant and immediate cognitive, immune, and mood improvements from my high-dose daily Broccoli Sprouts. I cannot evaluate my Autism symptoms so easily because I live a hermitage life, but I can definitively say I feel Great and I believe the commitment to Broccoli Sprouts is an integral part of my recovery (along with several other religious inputs including high-dose Omega 3/DHA, Red & Purple berries, garlic, multiple Vit/Min supplement). For all you reading this who wish to try this important experiment in your life (for Autism or Cancer), please consider this advice: 1) Buy ONLY “Organic” seed; Todd’s Seeds for bulk prices, and stored properly, will remain germinal for at least several years — if you can vacuum-pack them, longer (I am looking into this now); 2) Broccoli Sprouts are also in my Top 5 Prepper Foods List because this Kitchen Gardening “vegetable” can be produced underground, in a car, backpack lifestyle, without anything except a jar/screen + water; this means your purchase and self-training needs to be a top priority commitment now…..there is no other growing seed which takes priority for me, and this is coming from a retired Sustainable Vegetable Farmer who can grow anything anywhere. We will get sick fast on cooked, processed, “dead” food, some faster than others, because we must east raw plants every day to digest the rest and only raw foods will maintain life. Take your Sprouting self-training seriously and I am suggesting you start your process with Broccoli Seed Sprouts!
very interesting!! Where do you get your broccoli seeds??
I knew if old man Bush (HW) hated it, it had to be good!!
Is taking MSM supplements similar or same as sulfoarphane? I take msm daily for skin, nails and hair.