Reports have been circulating around the natural health community of a compound known as Gc-protein derived macrophage activating factor, or GcMAF, and its remarkable effects on cancer.

One of these is a video clip (above) of an in vitro attack of macrophages, a type of immune cell, which have been treated with GcMAF against human breast cancer cells. This can be best described by the common internet meme caption of “nom nom nom,” as the clusters of cancer cells are mercilessly devoured. Fortunately for humans, research on real patients has shown that its effects are not confined to a laboratory.

In human patients, however, GcMAF is not administered alone. In this study, GcMAF is described as being complexed with oleic acid (OA), which is found in olive oil. Additionally, the OA-GcMAF is prescribed alongside a low carbohydrate, high protein diet; vitamin D3, omega-3 fatty acids, low dose aspirin, and fermented dairy products containing naturally-occurring GcMAF.

Although these patients all suffered from advanced cancers, within a few weeks, their tumor volume had decreased by an average of 25%. While some clinical results were compared to chemo in tumor-shrinking power, OA- complexed GcMAF, along with some other types of OA- complexed proteins, destroys cancer cells without any ill effects on healthy cells.

One patient discussed in research is a 56-year-old man suffering from a recurrence of metastatic squamous cell carcinoma that was “successfully” treated with chemo and radiation. Because of his cancer’s location, OA-GcMAF was administered by both a nebulizer and subcutaneous injections. Even after only 5 days of treatment, ultrasonography had shown that his tumors had shrunk by approximately one quarter. He also reported improvement in breathing, with ventilation in the apical right lobe improving.

Related: Cancer-Fighting Foods – 4 Anti-Cancer Edibles

Another patient was a 62-year-old woman with “extensive” breast cancer and no history of conventional treatment. Within one week, the diameter of the two main lymph metastases (the primary tumor was unable to be measured due to size) shrunk from 3.9 to 3.46cm.

While GcMAF has anti-proliferative, anti-metastatic abilities, oleic acid has its own anticancer properties and may assist in binding to cell membranes. Together, they are 200 times more potent than GcMAF alone in destroying cancer cells in vitro. They also increase levels of nitric oxide, which has anticancer as well as antihypertensive properties.

Other documented cases show similar results. For example, a 63-year-old woman with colon cancer that later spread to her lungs and liver experienced a reduction in her liver tumor from 13 to 6.6mL in only 2 weeks of treatment! This was once again achieved by alternating nebulization and injection of OA-GcMAF.

Another patient was a 43-year old-woman with metastatic breast cancer to the bone and liver. After 1 week of both inhaled OA-GcMAF and that injected into her breast, her primary tumor shrunk from 1.8 to 1.3 mL, which was considered representative of four other cases.

Some are less dramatic, such as that of a man in his 30\s who experienced a reduction in one of his melanoma metastases from 52.1 to 48.6mm.

Overall, the use of GcMAF as a safe treatment alternative looks promising despite frightening stories of opposition. However, more evidence, whether scientific or anecdotal, is needed for a definitive conclusion. This is partly because of the lack of instruction on how to produce anything resembling OA-GcMAF at home (unlike the more well-known cannabis oil), which may either be unfeasible or undesired by those producing it.


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