These Commonly Prescribed Cholesterol Drugs Don’t Work
Turns out that type 2 diabetes patients taking a combination of drugs to lower bad cholesterol and increase good cholesterol might be wasting their time. Doctors have thought for many years that these drug combinations offer protection from heart attacks and improve survival, but new information shows that this method of treatment may have been ineffective. People suffering from Type 2 diabetes may have an elevated risk of cardiovascular disease, but these drugs aren’t the solution to such a problem.
Billion-Dollar Industry a Lie?
Three Food and Drug Administration panelists published a review of these drugs, called fibrates, in the New England Journal of Medicine.
“There have been a few studies regarding the clinical outcome efficacy of fibrates,” said co-author Sanjay Kaul, MD, director of the Cardiology Fellowship Training Program at the Cedars-Sinai Heart Institute. “Thousands and thousands of Americans take fibrates every day but so far, there are no long-term studies showing that fibrates lower cardiovascular risk or improve survival among diabetes patients who are also on statins.”
Common fibrates sold in the US include FDA-approved gemfibrozil (Lopid), fenofibrate (Tricor), and fenofibric acid (Trilipix), the sales of which amount to billions of dollars.
Kaul and fellow co-authors say there is more research to be done, and that in the meantime physicians should prescribe the statin-fibrate combination only to diabetic patients with a raised risk of heart attack, but only after statin treatment has managed LDL cholesterol levels. Seeing as they are FDA panelists, it isn’t surprising to hear them state this recommendation.
Related Read: Are Statins Safe?
Statins and Adverse Effects
Statins (also known as HMG-CoA reductase inhibitors) have been linked in peer-reviewed research to over 300 adverse effects, including cancer and liver damage. For those unwilling to take the risk and looking for a natural alternative to lowering controlling cholesterol, research reviewed by Loma Linda University shows that consuming a small bag of nuts daily reduces ‘bad’ cholesterol levels by 7.4 percent. (It is, however, worth noting that although independent researchers conducted the study, the Internationally Tree Nut Council Nutrition Research and Education Foundation partially funded them.) Nuts, however, are healthy in moderation, as long as you watch the additives that come with the package. Good options include:
- Omega-3-packed walnuts
- Selenium, vitamin E, magnesium, and calcium-rich almonds
- Copper, niacin, fiber, protein, and vitamin E-filled Brazil nuts
Don’t, however, go about thinking cholesterol is evil. Actually, cholesterol isn’t evil at all; read all about how millions have been deceived using the great cholesterol myth.
Struggling with diabetes or cardiovascular problems? Even if you’re not, it’s best to remember that prevention is the best medicine. Try
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You shold specify : Fibrates used in conjunction with statins in diabetes patients may be dangerous. I have used and prescribed them (alone) in hypertrygliceridemia (due to ingestion bad habits) with wonderful result and no side effects. The overall view of the article is OK.