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Genetically Modified HIV Vaccine Approved – Human Tests to Begin Shortly

Mike Barrett
December 21st, 2011
Updated 11/06/2012 at 11:28 pm
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bloodsample2 210x131 Genetically Modified HIV Vaccine Approved Human Tests to Begin Shortly

At a further attempt to halt the spread of HIV, the United States is making a bold decision to begin testing the HIV vaccine. Researchers from the University of Western Ontrario developed a new vaccine, and the Food and Drug Administration announced its approval on Tuesday for use in the US. Containing a genetically modified virus, the experimented vaccine is set to be tested on thousands of participants.

The Researchers have been studying HIV and AIDS for 20 years and have spent the last 10 developing the vaccine. Starting in January, the vaccine will undergo three phases of human clinical trials.

Phase I – The first phase is meant to analyze the vaccine and determine if it is toxic in the human body.

Phase II – During phase two of the human clinical trials the researchers will look at the immune response to see if the vaccine actually performs like it is supposed to by inducing the proper immune response.

Phase III – In phase three 6,000 people are needed so that statistical data can be accumulated and later presented. For the testing, a vaccinated and non-vaccinated group will be compared to see if the vaccine protects against HIV infection or not.

The vaccine raises alarms when considering the potential side effects and adverse reactions that may be experienced not only in the test group, but in the population as a whole. As with the experimental anthrax vaccine, the tests have become controversial in nature. With the anthrax vaccine, however, many experts and political figures were outspoken against the shot as it had been linked to death and serious side effects in previous government trials. In fact, the the 2007 CDC report that found “between 1 and 2 percent” of military personnel injected with the anthrax vaccine experienced ”severe adverse events, which could result in disability or death.”

About Mike Barrett:
2.thumbnail Genetically Modified HIV Vaccine Approved Human Tests to Begin Shortly Google Plus Profile |Mike is the co-founder, editor, and researcher behind Natural Society. Studying the work of top natural health activists, and writing special reports for top 10 alternative health websites, Mike has written hundreds of articles and pages on how to obtain optimum wellness through natural health.

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  • Anonymous

    It's like a circle jerk of hippies who are mad because they can't find proper jobs with their brainless English degrees. It's amusing how people are just blindly posting quotes without reading the actual papers behind them and understanding the statistical relevance of everything they're saying.

    Feel free to post proof that you've actually studied biology. A Bachelor's of Science from an accredited university would be a great place to start.

    • Anonymous

      im a molecular biologist, and im cheering this on hoping it works!

    • Sim Reilly

      Let's see.

      Anonymous says:

      December 22, 2011 at 6:42 am

      It’s like a circle jerk **snide remark** of hippies **name calling** who are mad **belittling** because they can’t find proper jobs **derogatory assumption** with their brainless ** judgement/put down** English degrees. It’s amusing **snide**how people are just blindly **rude assumption** posting quotes without reading the actual papers **rude assumption**behind them and understanding **put down/assumption** the statistical relevance **snide & belittling** of everything **ooh generalisation**they’re saying.


      Feel free to post proof that you’ve actually studied biology. A Bachelor’s of Science from an accredited university would be a great place to start.

      • Sim Reilly

        Feel free to post proof you can function as a human being and not just a chronic emotional abuser.

  • Marc

    "The US is in the midst of an epidemic of neurodevelopmental disorders (NDs). Thimerosal is an ethylmercury-containing compound added to some childhood vaccines. Several previous epidemiological studies conducted in the US have associated Thimerosal-containing vaccine (TCV) administration with NDs."

    Med Sci Monit. 2006 Jun;12(6):CR231-9. Epub 2006 May 29. PMID: 16733480

    As thimerosal was removed from childhood vaccines, the number of neurodevelopmental disorders decreased in the US……

  • More nonsense from t

    I love how you extrapolate how a single vaccine that shouldn't have been passed to be the same as every vaccine in existence and every vaccine that will be made.

    Dear sir, please explain to me how, in scientific terms, the Anthrax vaccine (made by attenuated bacteria) is at all similar to the HIV vaccine about to undergo human trials (made using genetically modified viruses)?

    The methods of vaccinations, the pathogens, everything is completely different except for the word 'vaccine' itself. And in your scientific illiteracy, you foolishly equated the two to being the same.

    Sir, you are lucky you have never taken a single biology or statistics course. You would have sorely failed both.

  • Anonymous

    Just an FYI to commenters: not only are many vaccines unsafe…. but this is EXPERIMENTAL!

    • More nonsense from t

      Of course it's experimental. Do you have a clue what experimental means? It doesn't mean "It's much more dangerous and will kill you", but "This is currently undergoing experiments".

      Would you rather the FDA release medicines without any proper human trials?

      The whole point of experiments is to figure out what exactly this vaccine does in humans. Trials in culture (using both human and non-human mammilian cells) and in-vivo have been performed, but for obvious reasons no analogue can perfectly mimic the human body and its many biochemical and immunological characteristics.

      The drug is experimental because the researchers need to see if it works, if it's safe, or if it's harmful before releasing it to the public.

      But the way this moron writing the article is making it out to be, he equates experimental = deadly and vaccines = deadly.

      The immense amount of lack of biological knowledge is astounding in this page. It's as if Natural Society prides itself on its writers pulling nonsense out of their buttocks.

      • Anonymous
      • Anonymous

        Microglia are the resident immune cells in the central nervous system. Normally they remain in a quiescent state. When stimulated, they become metabolically active and assume an ameboid profile, with an ability to move about the CNS. Activation of microglia is quite easy and can be accomplished by a number of events, such as trauma, excitotoxic excitation, invasion of microorganisms, heavy metal toxicity, systemic immune activation and various pharmaceutical agents.

        Under most circumstances this activation is short lived and terminates rather abruptly. Under such conditions, the microglia serves the function of any immune cell-that is, it releases immune cytokines, eicosanoids, free radicals, lipid peroxidation products and complement, which act to kill the invading organisms. In addition, microglia secrete several growth factors (brain derived growth factor and epidermal growth factor), which serves to repair any damage that might have been done. It also has ameboid, phagocytic activity, which allows these cells to remove cellular debris and dead or dying microorganisms. It can also remove soluble beta-amyloid, which can accumulate during such assaults. Because of their ability to move around and between neurons, they can specifically target the synaptic interface. In a great number of conditions, this synaptic unit is damaged and therefore is central to their pathophysiology.

        On occasion, the activation of microglia is not terminated and a state of chronic activation occurs. When this happens, significant damage can occur to a number of brain microstructures, especially synaptic connections and dendrites. While short term microglial activation can be neuroprotective (because of the secreted growth factors) chronic activation appears to be neurodegenerative. Newer studies have shown that chronic microglial activation occurs in a number of pathological states, including CNS trauma, infections, heavy metal toxicity, pesticide exposures. neurodegenerative diseases, autism, Down’s syndrome and over-vaccination.

        When microglia are activated, they also secrete two known excitotoxins-glutamate and quinolinic acid. In addition, they secrete a number of factors that are also known to enhance excitotoxicity, such as tumor necrosis factors-alpha (TNF-alpha), IL-1ß, IL-2, IL-4, IL-6 and IL-18, as well as interferons and other immune molecules. A number of studies have shown that several of these immune factors greatly enhance excitotoxicity, especially TNF-alpha and IL-1ß-two inflammatory cytokines that are elevated in all of the neurodegenerative diseases as well as autism.

      • Richard

        Hepatitis B vaccine alters the expression of 144 genes in the mouse liver within 1 day of vaccination, 7 of which are related to inflammation and metabolism.


        • Liam

          Here's another, Richard.

          38,787 adverse events including infant death (highest in 1-3 month olds) after vaccination were reported between 1991-1994. (The authors speciously claim SIDS and not vaccination caused these deaths) —

  • Anonymous

    We will soon see if this shot comes with a ton of side effects.

  • Someone who actually

    If you really want to be taken seriously, you should really research biology before publishing articles. Everything in this shows a level of understanding of molecular biology, immunology, and public health at a level below that of your average undergraduate, let alone the graduate-level knowledge required to even understand how this vaccine works.

    So to Mike Barrett and the rest of the folks at Natural Society: Please actually go to college and learn about biology before you spout nonsense like this.

    • Anonymous

      Right, because flu vaccines are actually 100% safe and effective. That's why flu shots have led to deadly nerve disease, are 1% effective, and Gardasil has lead to over 50 deaths.

      Great education!

      • Someone who actually

        No vaccine is 100% safe. Every human is different. There will always be adverse reactions. Anyone who expects every medicine to be 100% effective is an idiot.

        50 deaths. Tell me, how many doses were given? I'm willing to bet that you're going to get a <1% mortality rate, which is much lower than what you get from influenza itself.

        Again, feel free to educate yourself. It's obvious from your post you're either a homemom or a humanities major with an IQ lower than Bush's approval rating and absolutely no knowledge of biology whatsoever.

        Please, don't comment if your brain isn't functioning.

  • Anonymous

    I am happy about the news for this vaccine, but the writer really have no idea how vaccines work (I don't know much either, but general knowledge) and advice people to not sign up for the human test phases. I know the philosophy of the site, but this is bad way to present facts.

  • Anonymous

    ugh. learn something, even just a little bit before you start rambling nonsense.