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Common Spice May Reduce Tumor Size by 56%

Anthony Gucciardi
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September 13th, 2011
Updated 12/27/2012 at 7:11 pm
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Ginger, a commonly consumed spice found in food products and beverages worldwide, has been found to exhibit many anticancer benefits. According to a new study out of Georgia State University, whole ginger extract has been found to reduce prostate tumor size by 56% in mice. In addition, ginger is a powerful source of several bioactive phenolics, including gingerols, paradols, shogaols and gingerones.

GreenMedInfo reports on the study:

It is appreciated far and wide that increased and regular consumption of fruits and vegetables is linked with noteworthy anticancer benefits. Extensively consumed as a spice in foods and beverages worldwide, ginger (Zingiber officinale Roscoe) is an excellent source of several bioactive phenolics, including non-volatile pungent compounds such as gingerols, paradols, shogaols and gingerones. Ginger has been known to display anti-inflammatory, antioxidant and antiproliferative activities, indicating its promising role as a chemopreventive agent.

Here, we show that whole ginger extract (GE) exerts significant growth-inhibitory and death-inductory effects in a spectrum of prostate cancer cells. Comprehensive studies have confirmed that GE perturbed cell-cycle progression, impaired reproductive capacity, modulated cell-cycle and apoptosis regulatory molecules and induced a caspase-driven, mitochondrially mediated apoptosis in human prostate cancer cells. Remarkably, daily oral feeding of 100 mg/kg body weight of GE inhibited growth and progression of PC-3 xenografts by approximately 56 % in nude mice, as shown by measurements of tumour volume.

Tumour tissue from GE-treated mice showed reduced proliferation index and widespread apoptosis compared with controls, as determined by immunoblotting and immunohistochemical methods. Most importantly, GE did not exert any detectable toxicity in normal, rapidly dividing tissues such as gut and bone marrow. To the best of our knowledge, this is the first report to demonstrate the in vitro and in vivo anticancer activity of whole GE for themanagement of prostate cancer.

About Anthony Gucciardi:
1.thumbnail Common Spice May Reduce Tumor Size by 56%Google Plus ProfileAnthony is the Editor of NaturalSociety whose work has been read by millions worldwide and is routinely featured on major alternative and mainstream news website alike, including the powerful Drudge Report, NaturalNews, Daily Mail, and many others. Anthony has appeared on programs like Russia Today (RT), Savage Nation, The Alex Jones Show, Coast to Coast AM, and many others. Anthony is also dedicated to aiding various non-profit organizations focused around health and rehabilitation as well as the creator of the independent political website Storyleak

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